Thromboangiitis obliterans.

نویسندگان

I J Schatz

G Fine

W R Eyler

چکیده

Thromboangiitis obliterans (TAO) has been a recognized clinical entity for more than half a century (Buerger, 1908). Distal arterial occlusive disease and/or recurrent superficial thrombophlebitis occurring in an adult male smoker, in the absence of known cause, constitutes a distinctive and unmistakable syndrome (Brown, Allen, and Mahorner, 1928). However, the existence of this disorder has been questioned because it was not being encountered clinically, and meticulous examination of unselected amputated limbs did not reveal the characteristic microscopical changes (Wessler et al., 1960). For these reasons, it was suggested that the diagnostic category of thromboangiitis obliterans be discarded (Wessler, 1961). If the question of the existence of this disorder had no practical importance, arguments about it could be regarded as exercises in medical pedantry and be dismissed. We feel, however, that this syndrome is separate and distinct, and that failure to recognize it will deprive patients of correct advice and proper treatment. In our opinion, the lack of plentiful characteristic histological changes and the failure to detect such cases clinically are not sufficient arguments to deny what is a clear clinical syndrome. This study was undertaken to emphasize the clinical, radiographic, histological, and prognostic features of Buerger's disease and the differences from other forms of vascular disease.

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